Stop Replacing.
Start Reloading.
The world’s first reloadable epinephrine auto-injector. Designed for reliability, affordability, and assurance of being prepared.
Why Should Peace of Mind Expire?
The anxiety of an expired pen. The high cost of replacement every year. The fear of not being ready. We knew there had to be a better, more reliable way to manage anaphylaxis.
A smarter solution for
allergy emergencies.
A smarter solution for allergy emergencies.
Managing allergy emergencies can be challenging, especially considering you may have less than 15 minutes to act. Traditional auto-injectors are often complicated to operate, which can be overwhelming in a high-stress situation. They have a high risk of misuse and accidental injuries. They’re also costly and contribute significantly to environmental waste.
User-friendly
A simple mechanism makes the injection process straightforward and stress-free.
Budget-friendly
Using a reloadable cartridge design significantly lowers the cost of replacement.
Eco-friendly
The reloadable cartridge minimises waste, lowering their environmental effect.
Safe
Safety features help prevent accidental activation and reduce the risk of injury.
User-friendly
A simple mechanism makes the injection process straightforward and stress-free.
Budget-friendly
Using a reloadable cartridge design significantly lowers the cost of replacement.
Eco-friendly
The reloadable cartridge minimises waste, lowering their environmental effect.
Safe
Safety features help prevent accidental activation and reduce the risk of injury.
Designed for Safety.
Built for Sustainability.
Our device offers drug delivery as effective as leading competitors, with a design focused on reliability. Our clinical trials confirm the pharmacokinetics, and interchangeable needle lengths ensure it meets diverse patient needs.
12x
Lower Risk of Injury.
88%
More Affordable over a 5-year period.
122
Million plastic bottles saved. Reloadability means less plastic waste.
Proof You Can Count On.
Again and Again
More First-Try Success
75% more
First-time successes vs a leading single-use pen in an independent, randomised human-factors study.
Faster When Seconds Matter
30 seconds
Faster to first dose in a high-stress, simulated-use scenario.
Reload Between Expiry Dates
A fresh cartridge can be loaded at home in less than two minutes. Usability studies confirm that most participants can complete the critical reload steps with confidence.
Proven Epinephrine Delivery
Clinically comparable Epinephrine exposure to established auto-injectors (Cmax/tmax comparable; AUC comparable or higher within the standard 0.8–1.25 range).
Randomised simulated use with trainer devices; participants read instructions before tasks. PK performance was benchmarked against published literature for established auto-injectors. ZiBiPen is an investigational device and not yet authorised for sale
ZiBiPen: A More Thoughtful Design
We started by listening. The features you see below are our answers to the real concerns raised by families and clinical experts, offering a more intuitive and reliable design that makes essential care more sustainable by eliminating unnecessary costs.
Safety Mechanisms
Features a protective safety sheath that locks after injection to prevent needle-stick injuries, and a clear viewing window, allowing you to visually check for discolouration that indicates expiration.
Reloadable Cartridge
A cost-effective and sustainable design that allows the user to replace only the epinephrine cartridge annually, not the entire device.
User-Friendly Design
An ergonomic, non-slip grip and a simple two-step activation process make the device straightforward and easy to handle in an emergency.
Customisable Needle Depth
Offers various needle length selections to ensure effective Epinephrine delivery to the muscle, accommodating different body types.
Safety Mechanisms
Features a protective safety sheath that locks after injection to prevent needle-stick injuries, and a clear viewing window, allowing you to visually check for discolouration that indicates expiration.
Reloadable Cartridge
A cost-effective and sustainable design that allows the user to replace only the epinephrine cartridge annually, not the entire device.
User-Friendly Design
An ergonomic, non-slip grip and a simple two-step activation process make the device straightforward and easy to handle in an emergency.
Customisable Needle Depth
Offers various needle length selections to ensure effective Epinephrine delivery to the muscle, accommodating different body types.
"One of the decade's most exciting inventions..."
— Business Insider SA
A Globally Patented
Innovation
We pursued global patents for our reloadable technology not just to protect an idea, but to protect our mission. This ensures we can bring a more affordable and sustainable option to families everywhere who live with the reality of anaphylaxis.
Latest Press & Media
Stay updated on our milestones, partnerships and impact as we advance accessible emergency care across Africa through ZiBiPen.
22 May 2026
22 May 2026
20 April 2026
20 April 2026
FAQS
Have questions? We’ve compiled answers to some of the most common queries to help you better understand our devices.
How do you ensure the device’s durability and reliability?
We put ZiBiPen through extensive tests. It undergoes drop tests, extreme temperature and humidity testing, and lifecycle simulations to ensure it works in real-world emergencies. We use high-quality materials and strict quality control during manufacturing, so every device meets our high standards before it reaches you.
Have you conducted the necessary usability tests and clinical trials for the ZiBiPen?
Yes, usability testing is a critical part of our development process and we have successfully conducted human clinical trials to validate the effectiveness and safety of the ZiBiPen.
What are the advantages of the ZiBiPen being reloadable?
1. It’s much more cost-effective because you only need to replace the drug cartridge instead of the entire device. This is particularly important for medications like epinephrine (adrenaline), which have a limited shelf life.
2. It’s environmentally friendly, as it minimises medical waste.
3. It provides peace of mind – you know you can always have a fresh dose of medication on hand without the expense and hassle of buying a whole new device.
How easy is it to use a ZiBiPen?
We’ve conducted studies with different types of people of different ages using ZiBiPen under stressful conditions and everyone was able to use their ZiBiPen correctly even when they were stressed.
Where can I get the ZiBiPen?
Want to support us? Email info@impulsebiomed.com and tell us your story of allergy and anaphylaxis. Your experiences help us advocate for the urgency of getting ZiBiPen to market faster!
Get in touch.
Contact us for any inquiries or to learn more about our innovative ZiBiPen.
ZiBiPen is an Impulse Biomed Innovation.
Address
160 Sir Lowry Road, Unit 403
The Armoury Building
Woodstock, Cape Town, 7925